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Topina (Topiramate)

Topina is a medication that has been available for a long time to treat migraines and seizures. Based on new research findings, Topina is now being used “off-label,” or outside of its currently approved indications, to treat alcohol dependence. Specific circumstances, which your physician will discuss with you, may make this medication the first-choice treatment option. Exactly how Topina works in alcohol dependence is not known, but it is thought to reduce alcohol’s pleasurable effects and so helps people to abstain from alcohol.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Effects of calcitonin on function of intercalated cells of rat cortical collecting duct. Maternal mortality and derivations from the WHO near-miss tool: An institutional experience over a decade in Southern India.

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Neither the menopausal symptoms caused by therapy with gonadotropin-releasing hormone agonists nor the adverse androgen-related effects induced by danazol were observed. Redo coronary artery bypass surgery carries a higher risk for mortality and non-fatal myocardial infarction.

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Respondents reported that uninsured patients had greater difficulty obtaining access to off-site specialty services, including referrals and diagnostic testing, than did patients with Medicaid, Medicare, or private insurance. In four double-blind, placebo-controlled trials, nicorandil has been shown to produce beneficial haemodynamic effects in patients with stable angina pectoris without significant deleterious effects on pulse rate, the cardiac conducting system, myocardial contractility or myocardial oxygen consumption. The course, relations and branching of this suprarenal branch differed from the very rare cases found in the literature. We evaluated 30 prelingually deafened adult patients, 18 males and 12 females, median age 35 years, of a group of 36 prelingually deafened adult patients consecutively submitted to unilateral cochlear implantation at the ENT Unit of the University of Pisa.

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The influence of activation parameters such as ZnCl(2) to cattle-manure compost (ZnCl(2)/CMC) ratio, activation temperature and retention time on the final products was investigated. The authors also determined the frequency of bradycardia requiring anticholinergic therapy during anesthesia in dogs with glaucoma. Our group recently developed the first assay to quantify serum ApoA5 protein concentrations and demonstrated that they are increased by administration of a potent peroxisome proliferator-activated receptor-alpha agonist. The purpose of this study was to clarify the difference between RECIST version 1.0 and version 1.1 in advanced gastric cancer.

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An attempt is also made to evaluate the role played by such comparisons in quality measurement improvement in nuclear medicine, on the basis of results obtained in a number of countries and published by several authors over a period of time. The complement depleted rats had significantly lower levels of proteinuria, despite having more antigen and larger deposits in their glomeruli. For women, they were also from the oldest age class, but some of them were from the upper social class, with an ideal BMI and lived by the Mediterranean shore. Three roles emerged: knowledge broker, companion, and navigator. Treatments that target immune checkpoints, such as the one mediated by programmed cell death protein 1 (PD-1) and its ligand PD-L1, have been approved for treating human cancers with durable clinical benefit1,2.

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Right-sided varicocele may be almost as common as varicocele on the left and may be responsible for much of the bilateral effect of clinical left-sided varicocele. Antibiotic sensitivity of strains of the plague microbe isolated from foci in the Caucasus and Transcaucasia Comparison of four software packages for CT lung volumetry in healthy individuals. Adult age differences in implicit and explicit memory: time course and encoding effects. Furthermore, irradiated DC failed to acquire a full mature phenotype upon treatment with lipopolysaccharide.

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Taken together with previous findings implicating Cdc7 in meiotic DNA recombination and induced mutagenesis, these findings prompt us to postulate that the Cdc7 protein kinase regulates some step common to several DNA metabolic processes such as local disassembly of chromatin or activation of a key component of the DNA metabolic machinery. Thermal discrimination thresholds in normal subjects and in patients with diabetic neuropathy. Unfortunately, these files may fracture without any prior visible warning signs.

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The aim of this study was to investigate the length changes of SLIL at wrist full extension and forearm rotation in vivo. Both genetics and gender are important and interacting factors in the aetiology of nocturnal bladder control.

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Polyclonal antibody secretion in human lymphocytes induced by killed staphylococcal bacteria and by lipopolysaccharide. Biological studies have revealed that these viruses use mechanisms to either inactivate (adenovirus) or take advantage of (herpes simplex virus) the cellular DNA-repair machinery to achieve productive replication. In the proposed BRB-based model, the initial values of parameters are usually given by experts, thus some of them may not be accurate, which can lead to inaccurate prediction results. Wavelength-dependence of bilirubin photoconversion was studied within photoequilibrium and up to a large decrement of the total concentration.

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Ophthalmomyiasis in Kuwait: first report of infections due to the larvae of Oestrus ovis before and after the Gulf conflict. Funding sources and opportunities available to one party alone are insufficient. AC was calculated as SV/PP and adjusted to body surface area to calculate the SV/PP index (SV/PPi).

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A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans. Assessing the health of these personnel may help to improve their reproductive health. The main clinical and morphological criteria for a rabbit model of PVR induced by intravitreal injection of heterogenic fibroblasts have been established: epiretinal membrane formation, changes in intraocular structures (the retinal pigment epithelium and retina), and inflammation (due to transplantation immunity). Inspired by the precise Golgi positioning ability of galactosyltransferase and protein kinase D, due to their cysteine residues, we developed a method for long-term Golgi imaging.

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Their use in constructing a consensus protein model for ligand design is discussed. Physically blocking pili imposed resistance to pilus retraction, which was sufficient to stimulate holdfast synthesis without surface contact. We also found that reruptures of the supraspinatus that had been smaller than 400 mm(2) had the potential to heal.

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In Study 1, vegetable baskets (containing cut pieces of vegetables), fruit baskets (containing cut pieces of fruit), pretzels, and yogurt were promoted in separate POP interventions. Living systems are able to respond to external and internal stimuli rapidly and in a graded fashion by maintaining a pool of proteins whose activities are altered through post-translational modifications. To explore the importance of research topics among a diverse range of people living with any type of diabetes or caring for someone living with any type of diabetes.

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Thus, the earliest supraspinal, propriospinal, and ascending fiber connections appear to be formed almost simultaneously. These pictures which on the X-ray resembled initial osteophytes were found seven times on the head of the femur and fourteen times on the edge of the joint acetabulum.

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Because of the possible role of ischaemia in this condition effective control of prolonged tachycardia is needed to prevent deterioration of myocardial function. Finally, suppression of LPS induced MMP-13 mRNA levels resulted with CS. The data are based on individual interviews with 35 patients living in six nursing homes and seven focus group interviews with 60 relatives.

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Sudden unexpected death in epilepsy (SUDEP) represents a significant category of mortality in the population with chronic epilepsy. In order to understand the vascular abnormalities observed in smokers, we investigated vascular responsiveness in cigarette smokers.

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A total of 675 consecutive patients who underwent curative surgery for lung cancer in two specialized thoracic centers between 2007 and 2011 were included in this retrospective study. Low levels of IL-6 could be detected in the endometrium/epithelium on the second day and endometrium/myometrium on the third day of gestation. Using pyrrole as a representative substrate, only a single oxidation product, 4-pyrrolin-2-one, was observed, and notably without formation of polypyrrole. At diagnosis, phenylalanine and glutamic acid concentrations were elevated compared with previously published normal values and remained elevated at all observation times. These findings highlight the clinical and public health importance of CKD.

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Heart Failure With Reduced Ejection Fraction in Human Immunodeficiency Virus Infection: The More Things Stay the Same. Epinephrine and cortisol showed the clearest increase in serum and collected urine, whereas norepinephrine, prolactin, hGH and gastrin reacted less strongly. School-based survey participation: oral health and BMI survey of Ohio third graders.

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An In-vivo Prospective Study of the Diagnostic Yield and Accuracy of Optical Biopsy Compared with Conventional Renal Mass Biopsy for the Diagnosis of Renal Cell Carcinoma: The Interim Analysis. Dipyridamole and adenosine have a high side-effect profile, provide higher than needed coronary artery flow rates, and use a relatively complicated method of administration. Considering that, essentially, muscle endogenous enzymic activity, calpains and cathepsins, occur in the ripening process of dry-cured ham, whereas a combined action between endogenous and microbial enzymes takes place in the case of sausage ripening, these results provide deeper insight into the respective role of endogenous and microbial enzymes in performing proteolysis. The autoradiographic experiments provide evidence that these cells also possess high-affinity GABA uptake sites.

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Ocular circulation is regulated to maintain the homeostasis of retinal function in response to physiological stimulus. The grand jury and health care crimes: what every physician executive needs to know. Human Parturition Involves Phosphorylation of Progesterone Receptor-A at Serine-345 in Myometrial Cells.

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To solve the resulting set-cover variants, we modify the classical branch-and-bound algorithm to include some of these biological criteria. According to latest available data there are more of 300,000 people injects drug users (PWID) in Iran. Association of reciprocating and rotary files was capable of removing a large amount of filling material in the retreatment of curved canals, irrespective of the type of alloy of the instruments. Altered megakaryocyte-platelet haemostatic axis in hypercholesterolaemia.

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Industrial expansion in these cities is also a major contributor to the worsening air pollution. Efficient differentiation of patient-specific iPSCs into HSCs and progenitor cells is a potential means to overcome limitations of such cells for HCT, as well as for providing in-vitro drug screening templates as tissue-on-a-chip models. Moreover, the balance between proteolytic activity and inhibition is crucial in the metastatic event. A 17-year-old male with systemic lupus erythematosus presented with clinical signs of severe constrictive pericarditis that was confirmed by cardiac catheterization.

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Pneumothorax following transthoracic fine-needle aspiration of the lung. Besides questions addressing redundancy and diversity, more and more attention is given on the abundance of specific DNA and mRNA in the different habitats.

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Kinetic studies of Escherichia coli transfer RNA (uracil-5-)-methyltransferase. Using these parameters and previous locomotor EMG data, stimulation was performed on each joint muscle pair to produce reciprocal flexion/extension movements in the shoulder, elbow, and digits, while 3D joint kinematics were assessed. The adductor pollicis, and FPL were nearly equal during pinch and grasp, with significant electrical activity increasing with greater force requirements. The index events included vaginal disorders, vulvar disorders, uterine and ovarian factors, female genital organ and menstrual cycle disorders, menopause, and relative abdominopelvic organ disorders. Our findings therefore suggest that vortioxetine, alongside its antidepressive effect, may have immunomodulatory properties.

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Child sexual abuse and juvenile prostitution: a commentary on the Badgley Report on sexual offences against children and youth. Intracardiac echocardiography (ICE) may be an alternative imaging modality for LAAO that precludes the need for general anesthesia or sedation. On the basis of phylogenetic tree studies and informative positions, PLMVd variants are proposed to cluster into groups and subgroups likely to have resulted from recombination events. Social anxiety in late adolescence: the importance of early childhood language impairment.

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We found that the networks of ant-plant mutualists in twenty-five year old fragments are similar to those in continuous forest, suggesting these interactions are resistant to the detrimental changes associated with habitat fragmentation, at least in landscapes that are a mosaic of fragments, regenerating forests, and pastures. The advantages and limitations of using a self-monitoring procedure for improving performance of staff members in residential settings are discussed.

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Radiofrequency ablation of drug-resistant cancer cells using molecularly targeted carboxyl-functionalized biodegradable graphene. The most common organ involved was bladder in 33 cases, and next most common was kidney in 30 cases. Moreover, the Cu NCs were stable even in a high ionic strength medium such as 1M NaCl.

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Currently, on-chip integration of such antennas is hampered by their multielement design or the requirement of complicated excitation schemes. Two-dimensional rotating-frame nuclear Overhauser enhancement spectroscopy has been applied to milk oligosaccharides containing the blood-group determinants Lea, Led, or Leb.

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The microheterogeneity of carbohydrate moieties can be quickly screened using this approach for either tryptic digests or the intact glycoprotein. After hybridization with periodate-treated miRNA, the nanoparticle tags, isoniazid-capped OsO2 nanoparticles, are brought to the electrode through a condensation reaction to chemically amplify the signal. In addition, since this study analyzed results in the non-zero subgroup, clusters derived may be reflective of patients with poorer prognosis as these patients experienced all symptoms. The distribution of carbonic anhydrase (CA) in cerebrum, cerebellum and medulla oblongata of the cat brain has been examined by a histochemical method.

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Transesophageal echocardiography for evaluating left ventricular function Both photo-switch and superconducting bolometric behavior are monitored by its resistance change with light in visible and near infrared (NIR) wavelength range.

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Erythrocyte (red blood cell (RBC)) folate concentration was measured by chemoluminescence. Survival of Triple Negative versus Triple Positive Breast Cancers: Comparison and Contrast.

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This phenomenon, occurring at fast presentation frequencies of visual moving objects that are perceived as static, has not been previously explored by neuroimaging techniques. Transient and repetitive rises in blood pressure synchronized with plasma catecholamine increases after head injury.

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A 3-dimensional ground-truth map of stopping-power ratios (SPRs) was created for an anthropomorphic head phantom by assigning measured SPR values to segmented structures in a high-resolution CT scan. Medical vocabularies are, however, essential also for text mining from corpora written in other languages than English and belonging to a variety of medical genres. In India, the diversity of rotaviruses reported during the 1980s and 1990s emphasizes the need for surveillance of cocirculating strains, to follow the rapid changes in circulation and to detect novel strains. The argasid tick Ornithodoros moubata is a vector of various viral and borrelian diseases in animals and humans. Identification of a distinct class of vinblastine binding sites on microtubules.

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The results show that MCM-BP mainly interacts with MCM7 in the Triton-soluble fraction from S phase and G(2) phase cells, and it also interacts with structural maintenance of chromosome 3 in the fraction from G(2) phase cells. However, both Vpr and VprX were able to induce cell death in HeLa cells.

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An unusual complication following severe head trauma in two infants is described. Future work might include inducing remission with topical or oral corticosteroids and then randomising to doxycycline or prednisolone for maintenance. Junctional tachycardia has not been previously reported with fingolimod use. Liver stem/progenitor cells (LSPCs) are able to duplicate themselves and differentiate into each type of cells in the liver, including mature hepatocytes and cholangiocytes.

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All five clients showed significant decreases in aggression immediately after the implementation of the program. The possibility that the biosynthesis of some lignans may follow a radical cation mediated mechanism is discussed. We have shown how standard dimension reduction methods, such as PCA, can be used to help further interpret GSEA. The reaction rate is a function of the rotation rate and the mass of the balls. Electrical stimulation of cortical tissue could be used to deliver sensory information as part of a neuroprosthetic device, but current control of the location, resolution, quality, and intensity of sensations elicited by intracortical microstimulation (ICMS) remains inadequate for this purpose.

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The onset of drowsiness is preceded by an increment of antral distension and the duration of the symptom appears to be related to the persistence of antral distension. Isolation of alpha-amino adipic acid from mature dermal collagen and elastin.

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A comparative evaluation of the efficacy of diode laser as an adjunct to mechanical debridement versus conventional mechanical debridement in periodontal flap surgery: a clinical and microbiological study. The relationship between handedness, mechanism of injury and which hand injured. Determinants of a switch to another biologic agent for patients who are already on biologic treatment were also analyzed.

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Test examinations in social hygiene and public health administration The clinical manifestations range from intermittent and mild digestive problems to acute intestinal obstruction. Children less than 1 year admitted after cardiac surgery under cardiopulmonary bypass between November 2007 and December 2012. Effect of prostacyclin and 6-keto-PGFl alpha on coronary vascular resistance Despite in-vitro resistance of the organism to tiniazol shampoo similares nuevo amikacin sulfate, topical therapy with this antibiotic led to a complete cure without the need for surgical intervention.

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Persistent organ failure is a feature of severe acute pancreatitis (SAP) and the leading cause of death. Elastic parameters of aorta (aortic distensibility, aortic stiffness index) were calculated by predetermined formulas. A total of 143 patients were retrospectively evaluated, who had undergone a complete surgical resection for lung cancer less than 1 cm in diameter between January 1995 and December 2011. Supine VC may improve the detection of diaphragmatic involvement. Thigh muscle MRI in immune-mediated necrotising myopathy: extensive g tecta drug oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity.

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Syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis: HaNDL. Theoretical and experimental analysis of a linear accelerator endowed with single feed coupler with movable short-circuit. A case of Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD) was associated with small-cell lung cancer (SCLC). To facilitate a wide variety of coupling chemistries, the pendent carboxyl groups of poly(PEG-Lys) were converted to other reactive functional groups (amino, hydroxyl, active ester, telfexo 180 mg cena and aldehyde) in high yield. After radical prostatectomy, surgical margin positivity is an important indicator of biochemical recurrence and progression.

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The antivirual function of ifitm 3 in influenza A virus infection The identification of microorganisms with excellent tamsulosin erfahrungen smart flocculant-producing capability and optimization of the fermentation process are necessary for the wide-scale application of bioflocculants.

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This study determined the safety and activity of A(1-7) following chemotherapy in patients with breast cancer. This mode of B cell stimulation leads to proliferation of at least one per eight of human B cells and to a high topiramato 100 mg efeitos colaterais do viagra rate of antibody production. A fixation, an antisaccade and a countermanding saccade task were used to measure specific aspects of oculomotor inhibition. Pain and depression: a neurobiological perspective of their relationship.

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The midfacial degloving approach has been available for twenty five years and is slowly increasing in popularity in the management of extensive benign lesions of the sinonasal region, for selected malignancy in this area and to afford access to the nasopharynx and infra-temporal fossa. Three days after discontinuation of IFN-alpha, subjective symptoms and atrial fibrillation subsided. The cultured fetal cycline pour acne jeans Leydig cell provides a useful model to elucidate the molecular mechanism involved in the development of estradiol-mediated desensitization. The beta-lactamase activity of 510 recently isolated Enterobacteriaceae was investigated with a quantitative photometric test.

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Quantification by azithromycin 500 and alcohol isoform specific real-time PCR revealed higher expression of AKR1C1 in nine specimens and higher expression of AKR1C3 in four specimens of endometrial cancer. Ancylostoma ceylanicum, Ancylostoma duodenale, Necator americanus, Ancylostoma tubaeforme, Ancylostoma caninum and Uncinaria sanguinis as no work was reported yet.

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Qualitative evaluation and morphometry of the OSL were performed and results of all modalities compared. Mitral annulus calcification (MAC), while a relatively frequent autopsy finding in older patients, is rare in childhood. The first AND logic, the two inputs of which are the target enzyme and its substrate, is responsible for the accumulation of a phenol compound in cell. There is still no suitable mice model that can completely mimic the human fulminant hepatitis, which sets a block for drug effect evaluation and mechanism researching of human fulminant compraz tablet reviews hepatitis. To everything there is a season: hospitalizations in Ontario demonstrate strong evidence of seasonality and predictability.