Tadalafil is used to help men with erectile dysfunction to achieve and maintain a strong erection in response to sexual stimulation. The active ingredient Tadalafil is a PDE-5 inhibitor, which works by blocking a chemical in the body, known as phosphodiesterase type 5. It increases blood flow to the penile area providing an erection. Tadalafil stimulates the release of nitric oxide (NO) in the corpus cavernosum in response to sexual stimulation. Nitric oxide activates the lyase enzyme which results in increased levels of cyclic guanosine monophosphate (cGMP). This relaxes smooth muscles in blood vessels of the corpus cavernosum, increasing blood flow and thus inducing an erection. Tadalafil is the only PDE-5 inhibitor approved for the treatment of BPH (benign prostatic hyperplasia). By inhibiting PDE-5, Tadalafil allows for vasodilation and relaxation of the smooth muscle of the prostate and bladder, which thereby improves symptoms of BPH. Tadalafil as a treatment of premature ejaculation (PE) is usually suggested only when men with premature ejaculation also seem to suffer from erectile dysfunction. Tadalafil is also used in the treatment of PAH (pulmonary arterial hypertension).
Other names for this medication:
Tadalafil,
Adcirca,
Apcalis,
Cialis,
Femalefil,
Forzest,
Ladialis,
Snafi,
Tadacip,
Tadalafilo,
Tadalis,
Tadalista,
Tadapox,
Tadora,
Vidalista,
Zydalis,
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