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Overall survival (OS) was estimated using the Kaplan-Meier method and the log-rank test was used for comparisons between groups. All impressions and stone models were scanned using a laser scanner (Planmeca Planscan, E4D technologies), and 36 lithium disilicate (IPS e.max CAD) crowns were milled. Here we show that platelet-derived growth factor (PDGF) can replace type-1-astrocyte-conditioned medium in restoring the normal timing of oligodendrocyte differentiation in vitro and that anti-PDGF antibodies inhibit this property of the appropriately conditioned medium. The predictive value of different premorbid disorders was estimated. Estrogenic regulation of proenkephalin mRNA expression in the ventromedial hypothalamus of the adult male rat.

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The presence and distribution of oestrogen and progesterone receptors have been investigated by means of immunohistochemical procedures in the uterus of two groups of cows: the first group underwent superovulatory hormonal treatment while the second group was used as a control group. Comparative analysis of molecular activity in dermal mesenchymal stem cells from different passages.

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Classically it is characterised by sensorineural hearing loss and enlargement of the thyroid gland. Laminin and type IV collagen proteins of muscle fiber basal laminae were preserved after the detergent treatment. Aging changes and gender differences in response to median nerve stimulation measured with MEG.

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Candidate screening revealed that acetylation state of lysine 243 on BubR1 (BubR1-K243, an integral part of the spindle assembly checkpoint complex) functions during oocyte meiosis, and acetylation-mimetic mutant BubR1-K243Q results in the very similar phenotypes as Sirt2-knockdown oocytes. Do patient decision aids meet effectiveness criteria of the international patient decision aid standards collaboration? Cells and cell debris partition into the lower (PVA) phase over the pH range 4.8-7.5, and with up to 0.37 M KCl at pH 5.9. This paper reports results from a comprehensive review of factors that affect compliance with MDA. Regulation of human erythrocyte metabolism by insulin: cellular distribution of 6-phosphofructo-1-kinase and its implication for red blood cell function.

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Extensive digestive localization in a case of chronic lymphocytic leukemia: efficacy of radiotherapy An investigation of bonding systems for the polycarbonate crown restoration. Secondary thoracotomy enabled removal of an intrabronchial needle. The risk for depression associated with CSA was unaffected by quality of adult relationships, while the risk associated with poor parental care was substantially altered.

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We evaluated the relationship between oxidative health and reproductive effort in a free-living population of the cooperatively breeding Florida scrub jay Aphelocoma coerulescens. Jejunojejunal intussusception, requiring resection, was found at celiotomy. Choosing measures of health status for individuals in general populations.

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The significance of alterations in left ventricular shape that occur during dynamic exercise has not been investigated. FOXP3 encodes a novel member of the forkhead family of transcription factors.

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Primary survey data were collected in 1995 in a large nationwide study within 15 fields of health care and health care-related social services in The Netherlands. This study reviews the 26 patients who have had their disease recur, and who have evaluable diagnostic studies to examine for probable causes of recurrence. It is reasonable to assume that LEV may influence the metabolism of attention and of language area, as already suggested for piracetam (PIR) from which LEV derives. Past and current achievements in tissue engineering of microvasculature to perfuse organ specific constructs, small vessels for dialysis grafts, and modified synthetic and pediatric large caliber-vessel grafts will be discussed.

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Our results are compared with the other reported studies, and the possible role of these heteromorphisms in ethnic/racial variation and in developmental disturbances are discussed. Evidence for a surface receptor for human migration inhibitory factor on a B-lymphoid cell line. Since this guanine residue is not protected in open complexes, we conclude that its modification causes alteration of, or interference with, a transient contact during the transcription initiation pathway.

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Desymmetrisation of aromatic diamines and synthesis of non-symmetrical thiourea derivatives by click-mechanochemistry. A complex multiplication pattern of C4A and C4B genes with variations in gene size, gene dosage and flanking genes exists in the population. The differential effect of anti-A and anti-P implies differences in antigenic determinants between these two leishmanial forms. The POCIS sorbent was extracted and analyzed via high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS).

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We constructed radial flow displays which simulated 1 Hz horizontal linear head oscillation (generates motion parallax) or angular head oscillation in yaw (generates no motion parallax). The social feeding strain, npr-1(g320), was exposed to antipsychotic drugs, dopamine or calmodulin antagonists on plates with bacterial lawns, and the number of aggregates on the plates was counted as a measure of social feeding. The peptide neither leached from the membrane nor was cleaved by the medium-splenocyte mixture. Some professional football players who believed they had suffered a concussion chose not to seek medical attention at the time of injury. Access to orthopaedic spinal specialists in the Canterbury public health system: quantifying the unmet need.

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Histone deacetylase 3 suppresses Erk phosphorylation and matrix metalloproteinase (Mmp)-13 activity in chondrocytes. It was predominantly composed of complex, closely packed tubuloglandular structures but in few areas papillary structures were also observed. To study the influence of kainate receptors on trigeminovascular neurotransmission, we determined the presence of GluK1 receptors within the trigeminal ganglion and TCC with immunohistochemistry.

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Common carp (Cyprinus carpio) and brown trout (Salmo trutta fario) spermatozoa were exposed to either sodium dodecyl sulphate (SDS, anionic surfactant) or octoxynol 9 ( Triton X-100, nonionic surfactant). Infection associated with PVCD placement is uncommon but is an extremely serious complication. Mitochondrial pyruvate carrier 1 mediates abscisic acid-regulated stomatal closure and the drought response by affecting cellular pyruvate content in Arabidopsis thaliana. Based on data from pharmacogenetic trials, a combined analysis of multiple genetic variants in several genes is more likely to give significant results than single gene studies in small cohorts. Distant Metastasis and Survival Outcomes after Computed Tomography-Guided Needle Biopsy in Resected Stage I-III Non-Small Cell Lung Cancer.

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A case of pulmonary tuberculosis complicated with drug toxicosis--value of shosaikoto and hochuekito as anti-allergic agents A considerable amount of research has focused on elucidating the mechanisms by which cytokines synthesized by cells of the innate immune system participate in the life-threatening multiple-organ failure of endotoxic shock.

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Our hypothesis is supported by recent findings from two separate fields of research-population genetics and psychoneuroimmunology. However identification of these disorders can present difficulties and may call for additional training for professionals involved in the developmental screening of children in that age group. This study demonstrates that the needle driver is an effective option that offers advantages over surface drivers for obtaining accurate stiffness estimates in targeted regions that are accessible by the needle. Cognitive models of post-traumatic stress disorder (PTSD) posit that negative cognitions regarding the self and the world underlie the disorder.

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Statistical mechanical models can be used to analyze the observations to determine the fundamental energetic parameters governing the observed thermodynamic behavior. Box-loop ligament reconstruction of the elbow for medial and lateral instability. Service quality of delivered care from the perception of women with caesarean section and normal delivery.

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Our findings demonstrated that AT-101-induced autophagy was cytoprotective rather than being part of cell death process in lung cancer cells. In addition, an increase in mean cartilage water content and 35SO4(-2) incorporation into proteoglycans by 10 and 14 weeks, respectively, were consistent with the chemical changes observed in early osteoarthritis. In order to identify a protein that regulates the function of MKL1, we performed yeast two-hybrid screening and isolated cDNA that encodes UBC9, an E2 enzyme of small ubiquitin-related modifier-1 (SUMO-1), as an MKL1-binding protein. An accumulation of Lyt-2(-) and L3T4 lymphocytes was seen in the tumor tissue which was treated with IL-2 liposomes.

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FGF signaling inhibits chondrocyte proliferation by activating multiple signal transduction pathways that all contribute to chondrocyte growth arrest and induction of some aspects of differentiation. Parabiosis with genetically obese mice implied that ob/ob mice did not produce the feedback signal and subsequently the mutant ob protein, leptin, was identified. Comparison between numerical and experimental data for this case showed good agreement. Modified epidermal lipid composition in air-exposed culture of non-bullous congenital ichthyotic erythroderma (NBCIE) keratinocytes. Odorous volatile organic compounds (VOC) and hydrogen sulfide (H2S) are emitted together with ammonia (NH3) from manure slurry applied as a fertilizer, but little is known about the composition and temporal variation of the emissions.

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Assessment of vocation of rifabutin and rifapentine in replace of rifampcin in drug resistance leprosy patients: a molecular simulation study. In Chile, a country with a so called emerging market-economy, where rapid social and life style changes are taking place, women and the more socially disadvantaged are more at risk of becoming depressed. The structural and physicochemical characteristics are associated with resistance of plant cell walls to saccharification by enzymes.

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We succeed in reproducing the experimental results qualitatively with our model. Our previous studies have shown that human breast tumor cells rapidly shed membrane vesicles containing matrix metalloproteinases (MMPs).

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The galactosyl ceramide/sulfatide receptor binding region of HIV-1 gp120 maps to amino acids 206-275. Fine needle aspiration cytology in lymphadenopathy of HIV-positive cases. Two months after initial consultation, when the diagnosis was still elusive, an open lung biopsy was performed and the patient was treated with prednisone for 3 months. Neuroendocrine tumors with epithelial and nonepithelial elements are rare in any site and have not been reported in the lung. Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

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Crystalline lens radii of curvature from Purkinje and Scheimpflug imaging. Phonological awareness, reading accuracy and spelling ability of children with inconsistent phonological disorder.

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Response to preoperative chemotherapy, resection margin, and rehepatectomy for intrahepatic recurrence are key prognostic factors. To test the hypothesis that SR-A activity leads to proatherogenic changes in nonmacrophage cell lines, we generated Moloney murine leukemia virus- and vesicular stomatitis virus G protein-pseudotyped retroviruses containing SR-A type II cDNA, which were used for stable transfection of SR-A activity into mouse fibroblasts and rabbit aortic smooth muscle cells (SMCs). Evaluation of the prevalence of malignancy in DM at our clinic and search for characteristics of the paraneoplastic form of disease. The facile fabrication of superhydrophobic surface with enhanced drop mobility may find many practical applications including anti-icing, dropwise condensation and self-cleaning. THE VALUE OF PRELIMINARY COLOSTOMY IN THE CORRECTION OF GASTROJEJUNOCOLIC FISTULA.

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Peripheral electrical stimulation at high intensities sufficient to activate nociceptive sensory fibres elicited EPSPs within the ACC. In secondary (rarely primary) disorders of libido, erection and ejaculation, character neuroses, neurotic partnership conflicts on a pre-oedipal level as well as narcissistic crises in middle age were found. An interaction proteomics approach and the following co-immunoprecipitation experiments identified the nuclear import receptor importin-7 as a molecule that associated with EZI and, importantly, short interfering RNA-mediated knockdown of importin-7 expression completely abrogated nuclear accumulation of EZI.

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Interaction between the melanocortin-1 receptor and P genes contributes to inter-individual variation in skin pigmentation phenotypes in a Tibetan population. On May 8, 1986, a 61-year-old female was referred to Mito National Hospital for evaluation of a left-sided hemiparesis and headache 8 days after minor head injury.

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This review summarizes the differences in clinical outcomes following cardiac surgery according to gender. Several of his liver enzymes were elevated 10 times the upper limit of normal. These results indicate that salt-mediated osteopenia is due to an increase in bone resorption, rather than to a decrease in bone formation. All of the compounds tested displayed were inactive against the estrogen receptor-negative breast carcinoma lines. 99mTc-pertechnetate scan showed a round-like high radioactive concentration at the ileocecum.

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Comparison of perioperative outcomes between robotic and laparoscopic partial nephrectomy: a systematic review and meta-analysis. Solid-state circuit for spin entanglement generation and purification. Taken together, these data point to a central role for the ROC/GTPase domain of MASL1 in the regulation of its cellular function.

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However, treatment with pharmacological inhibitors of the nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt pathways sensitized endothelial cells to nutlin-3-induced apoptosis. Increased NO production from iNOS expression contributes to myocardial dysfunction and mortality after MI in mice. The focus of this review is to identify suitable animal models and insights into cardiovascular disease achieved to date using such models. Optimizing the management of brain-dead organ donors, including the possibility of selective administration of adrenergic agents, may provide a major benefit on graft survival without adverse side effects for the recipients. Rats were subjected to the standard four-vessel occlusion model of brain transient ischemia for 30 min.

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The case of a large solid hemangioblastoma embedded wholly in the medulla oblongata is reported. The influence of donor-related factors (donor age and sex, ischaemia time), recipient-related factors (recipient age and sex, frequency of acute rejection), type of immunosuppression (cyclosporin/azathioprine or prednisolone/azathioprine), and frequency of hypertension on left ventricular function one year after operation was examined by univariate and multivariate analysis. The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement study.

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RATIONS FOR THE STUDY OF THE RELATIVE NUTRITIVE VALUE OF FATS AND OILS. Because of these findings, we supported more aggressive treatment of the seizure disorder. Our results showed ISBBA, which uses unpurified antigen, to be more sensitive than the neutralization assay and ELISA for the detection of toxin B antibody.

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Information on antibodies for these analyses are also provided, which is an important consideration when attempting to use anti-human antibodies for the study of nonhuman primates. Tailoring the supramolecular structure of amphiphilic glycopolypeptide analogue toward liver targeted drug delivery systems.

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Anti-VEGF therapy is a promising new avenue for the treatment of ocular neovascular diseases. Here, I synthesise a mapping from each linguistic processing domain to a unique set of subserving oscillatory mechanisms-the mapping is plausible given the role ascribed to different oscillatory mechanisms in different subfunctions of cortical information processing and faithful to the underlying electrophysiology.

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Nausea and vomiting after strabismus surgery in preschool children. As the pressure observed at rest did not differ between the successful esophageal speakers and the unsuccessful esophageal speakers, and the amplitude, the duration of the pressure wave, and the area under the amplitude x duration curve were also equal for both groups, we conclude that the cricopharyngeal segment pressure is not a preponderant factor for the acquisition of esophageal voice and speech.

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With or without cryotherapy, eyes with severe ROP showed substantially poorer CS than did eyes of preterm children who did not develop ROP. Although this does not preclude a role for some family members in regulating gene expression, the contention that these sequences are transcribed tissue-specifically is not proof of such a role.