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The blind docking results rescored with both Amber and Rosetta yield docking funnels, i.e., three or more near-native structures among the top five predictions. Inactivation of multidrug resistant (MDR)- and extensively drug resistant (XDR)-Mycobacterium tuberculosis by photodynamic therapy. Thirteen patients required long-term intravenous antibiotics and/or multiple surgeries and incurred medical expenses in excess of dollar 77,000. NGTS was administered for 24 weeks to achieve target BP of 140/90 mmHg. This classification scheme has been shown to have relevance to clinical prognosis.

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In this study, the ability of different classes of antidepressant drugs (escitalopram, fluoxetine, paroxetine, sertraline, imipramine, tranylcypromine, and tianeptine) to mediate the expression of synaptic proteins and dendritic outgrowth in rat hippocampal neurons was investigated under toxic conditions induced by B27 deprivation, which causes hippocampal cell death. Our data implicates on the other mechanism of these disturbances. Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration.

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Knowledge gained through this review will eventually guide future research and interventions designed to enhance individual motivation and capacity to pursue STEM careers, particularly for females who are interested in STEM but may be constrained by misinformation or stereotypes. We have used the gerbil to study the ontogeny of a number of reflexes and locomotor acts to see if their sequence of appearance, their maturation, as well as their intensity of expression, differed from some other mammals. Nitric oxide in the pathophysiology of retinopathy: evidences from preclinical and clinical researches. The sTLR2 serum level in T2D patients was reduced despite elevated inflammatory parameters.

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Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Application of automated Edman degradation to the covalent structural analysis of proteins has had an important impact upon the generation of structural information. The novel CMCF algorithm significantly reduces the computation time required to estimate the scatter distribution by reducing the statistical noise in the MC scatter estimate and limiting the number of projection angles that must be simulated.

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To compare the results of two software-based methods, Quantra and Volpara, for volumetric breast composition assessment. This study investigated how metastability, defined as the standard deviation of synchrony described by the Kuramoto order parameter, arises from the structural connectome and relates to empirical measures of metastability in resting-state brain networks. Despite the strong relationship between smoking and health-related consequences, very few smokers quit. 9A3 antibody (IgG1, kappa) strongly reacted with various carcinomas immunohistochemically, but did not react with any normal tissues of the whole body tested except for neutrophiles and macrophages. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.

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To describe the characteristic clinical features and the diagnostic findings in muscle histochemistry of multi-minicore disease in 5 children from two unrelated families in Kuwait. Heterotrimers composed of collagen type IV alpha 1 (COL4A1) and alpha 2 (COL4A2) constitute one of the most abundant components of nearly all basement membranes.

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Elevation of HDL cholesterol, following adenoviral apolipoprotein A-I (apo A-I) gene transfer, may delay or revert ischemic cardiovascular disease, provided transgene expression is persistent. This technique may avoid detrimental hemodynamic decompensation, which may accompany regional coronary ischemia during cardiac displacement. New combination strategies based on the understanding of resistance mechanisms and intracellular feedback loops should be studied further in the future. Efficacy of a low-dose two-drug regimen of oral cyclosporine and delayed alternate day prednisone for immunosuppression in cadaver kidney transplantation.

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The aim of this study was to analyze solid-organ tumor frequency and characteristics in a population of lung transplant patients and provide a brief review of the literature. RNA interference (RNAi) was used to knock down the core circadian clock genes and to then assess the impact of the various clock genes on the ability of females to enter diapause. Rotatory evoked potentials in normal and labyrinthectomized rabbits. Are the symptoms and severity of head injury predictive of clinical findings three months later? Spinal tuberculosis represents a challenging disease to treat, not because of the technical expertise or the time required to cure it, but more so because of the decisions involved to treat it.

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A 69-year-old woman presenting with dyspnea had a pericardial window created for fibrinous pericarditis. We reviewed four cases of acute or subacute subdural hematoma associated with moyamoya phenomenon and emphasized the possibility of occurrence of acute or subacute subdural hematoma due to rupture of vault moyamoya vessels. Clinical preference for factors in treatment of geriatric depression. The clinical features of patients with adult-onset solitary mastocytoma are summarized.

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