Nefoxef is a selective, non-sedating H1 receptor antagonist, marketed in the United States since 2000. The FDA approved an oral suspension in 2006, for the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria in children. The tablet, capsule, and oral suspension are bioequivalent. Although Nefoxef does not use P450 CYP 3A4 it does interact with a number of drugs at P-glycoprotein and organic anion transporter polypeptides. The risk of toxicity from other drugs may increase with the administration of Nefoxef. Orange and grapefruit juices reduce the bioavailability of Nefoxef.
Other names for this medication:
Fexofenadine,
Aerodan,
Allerfex,
Allerstat,
Altiva,
Axodin,
Drusa,
Feksine,
Fenadex,
Fenadin,
Fenax,
Fenixa,
Fexidine,
Fexo,
Fexodine,
Fexofast,
Fexofen,
Fexofenadin,
Fexofenadina,
Fexotabs,
Histafree,
Histaloc,
Nefoxef,
Rinolast,
Telfast,
Telfexo,
Xergic,
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Makrodex,
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Zosec,
Bacterol,
Lopraxer,
Mebendazole,
Topcef,
Klabax,
Synergin,
Dazomet,
Prospera,
Acyrax,
Zimox,
Nortin,
Esoz,
Lansohexal,
Polypen,
Progen,
Valosine,
Grenis,
Plagerine,
Icoz,
Zocef,
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Increased sister chromatid exchange frequencies in lymphocytes of nurses handling cytostatic drugs. Both rotor and stator subunits are necessary for efficient taxim o dry syrup alkemites binding of F1 to F0 in functionally assembled Escherichia coli ATP synthase.
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