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Mycoderm (Ketoconazole)
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Ketoconazole

Mycoderm is a synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Mycoderm inhibits sterol 14-a-dimethylase, a microsomal cytochrome P450-dependent enzyme, thereby disrupting synthesis of ergosterol, an important component of the fungal cell wall.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. The use of ProDesign Logic 50/.01 files significantly reduced the amount of filling material at the apical levels compared with the use of reciprocating files.

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Rupture of the left ventricular free wall: a predictable complication of myocardial infarction? THE SURGICAL TREATMENT OF CHOLELITHIASIS, CHOLECYSTECTOMY AND CHOLEDOCHOTOMY: CONTINUOUS OUT-DOOR TREATMENT. A unique array-based pathogen chip has been developed for the detection of viral RNA or DNA relevant to pathologies of the central nervous system. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. To evaluate the clinical reliability of narrow implants placed in a one-stage procedure and early loaded in the upper and lower incisor region.

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These results provide clues for understanding the mechanism of TPP-induced stress and cytotoxicity on E. Effectiveness of intraoperative somatosensory evoked potential monitoring during cervical spinal operations on animals with spinal cord dysfunction. The observations corroborate those obtained in sectioned material as regards the geography of the CC response and the origins of new CC during the sodium iodate retinopathy, and provide new information on the way in which CC regenerates. Barriers to healthcare: Instrument development and comparison between autistic adults and adults with and without other disabilities.

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An Evaluation of Portable Wet Bulb Globe Temperature Monitor Accuracy. From this result, detection of MTB from circulating cell free DNA with this technique can be exploited as a less invasive diagnostic tool for pulmonary and extrapulmonary MTB infections. It is shown that the use of the simplified model based on the symmetric-top approximation allows roughly consistent simulation of the observed (CO(2))(2) dimer spectrum.

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Valine homozygous 129 PrP genotype in a French growth-hormone-related Creutzfeldt-Jakob disease patient. After extraction of the mandibular right first and second molars and healing of the sockets, a removable prosthesis replacing these teeth was fabricated and scanned. These constructs are examined in tandem with detailed clinical material taken from the psychotherapy of a seven-year-old boy and his two mothers. From another aspect, the presence of either the apolipoprotein E 2 or 4 alleles may cause an increased vulnerability to a slight chronic hypoperfusion of the white matter by reducing the range of mechanical and chemical flexibility of the glial cytoskeleton.

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Breast cancer patients were injected intravenously with 125I (74 MBq) labeled NR-LU-10 Fab (5 mg) and then underwent tumor excision 2, 4 or 7 days later, during which time the gamma detector probe was used to evaluate the primary tumor for evidence of radioactive uptake. Combined Measurement of Soluble ST2 and Amino-Terminal Pro-B-Type Natriuretic Peptide Provides Early Assessment of Severity in Cardiogenic Shock Complicating Acute Coronary Syndrome.

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Microsporidia, a group of amitochondriate organisms currently under intensive study, is not supported as derived within the Fungi, but a fungal affinity cannot be ruled out. Particularly during one of the most distinctive forms of acute respiratory failure, acute respiratory distress syndrome (ARDS), a tremendous impairment of the lungs occurs characterized by heterogeneous damage where normally aerated areas coexist with consolidated and collapsed areas. RECENT CLINICAL AND PATHOLOGICAL OBSERVATIONS ON GIANT-CELL MEDULLARY BONE TUMORS.

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In addition, conditioned medium collected from SNB19 cells transfected with these expression vectors showed diminished MMP-9 activity in the presence of phorbol myristate acetate, as determined by gelatin zymography. Medullary thyroid carcinoma occurs either sporadically or as part of the inherited MEN II syndromes.

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Black-blood pool imaging with double-inversion recovery sequence also helped to visualize the abnormal areas by showing slow flow artifacts in the four- and two-chamber images. Epithelial changes of the nasal columella of the palatal slit and cleft palate defects in C57BL/6 mouse fetuses.

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A synthetic peptide from this part of ICAM-2, covering residues 21-42, bound to purified CD11a/CD18 and inhibited the adhesion of endothelial cells to this integrin. The aim of this split-mouth animal study was to describe variable trends of biomarkers during the progression of peri-implantitis and to define relationships among CyPA, Emmprin, and peri-implantitis. Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat. It is thought that the lesions were due to anoxia secondary to compression of the nerve by a self-retaining retractor blade. Predicting school nurse involvement in meeting sexuality related needs of youth in New Jersey.

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As secondary analysis patients from each arm were stratified into subgroups with pelvic venous pressure less than 5 mm Hg, or 5 or greater as measured after cystectomy, which is the optimal cutoff for identifying patients with relevant blood loss according to the Youden index. After ratings (1 to 4) are assigned to each of the 7 indicators, overall nutritional status for each patient is determined by an algorithm. While most appear heterogeneous, some may appear homogeneous, but will likely reveal attenuations greater than 20 HU when multiple, small ROIs are used. hMSCs migrated from CEP towards the lesion area and significantly increased expression of collagen type II and aggrecan in IVD, namely in the nucleus pulposus. This review will focus on newly proposed functions of MTs and their implications relevant to diabetes and its complications.

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Late-onset schizophrenia is characterized by paranoid symptomatology, a high female:male ratio, an elevated prevalence of hearing loss and ocular pathology, schizoid or paranoid traits in premorbid personality, a tendency toward chronicity, and symptomatic improvement with neuroleptics. This papillary and cystic lesion shares similarities with papilliferum hidradenoma and mammary fibroadenomas. LOH burden may indicate vulnerability to treatment targeting DNA repair, such as PARP1 inhibitors. Zoonotic agents and genetically based resistance conferred by the Tyr139Cys polymorphism are both unevenly distributed in Lower Saxony.

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The results of this study confirm the association between ATI and AP among people 65 or older, also a progressive increase in the incidence of these diseases. Grapefruit juice (GJ), a cytochrome P450 (CYP) 3A4 inhibitor, may affect the pharmacokinetics of drugs metabolized through CYP 3A4.

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The rapid rise in rates of FR-TBI and associated Medicare costs underscore the urgent need to prevent this burgeoning source of human suffering and health care utilization. An additional aim of the study was to compare diagnostic imaging and histopathological findings and identify similarities between human and canine chronic post-traumatic spinal cord lesions. This study demonstrates that MTR histogram analysis allows better detection of early and subtle brain changes in ALL patients who receive MTX therapy than conventional MRI. In a controlled setting, we tested dietary preferences of Deltochilum verruciferum Felsche by offering one or two resources simultaneously. The low copy number plasmid R100 carries the pem region, consisting of two genes, pemI and pemK, which are required for stable maintenance of the plasmid.

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Successful reimplantation of a patch on a ventricular septal defect in a complex of measures for preventing early postoperative sepsis It seems reasonable to speculate that the mass of the tissue lump had become well balanced so that the very low pitch of the false vocal fold and a high pitch as in head register phonation could be avoided. The total GSH and GSSG content of parathyroid cells was found to range from 1.59 to 1.71 micrograms/mg cell protein, and this did not vary significantly with changes in extracellular calcium. Micropropagation and Subsequent Enrichment of Carotenoids, Fatty Acids, and Tocopherol Contents in Sedum dasyphyllum L. The problem involves a subtle interplay between nonlinearities and noise, and a naive approximation scheme that does not take this into account is shown to be unsatisfactory.

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Specific virulence to match this resistance is almost invariably present in pathogen collections. Recently, several pieces of evidence have been provided for a central role of NF-kappaB in NSC proliferation control. For convenient data sharing, Arthemis allows annotation according to the European Gastrointestinal Society for Endoscopy (ESGE) Minimal Standard Terminology (MST), an internationally accepted standard for digestive endoscopy. The retromuscular reconstruction procedure according to Rives appears to be an appropriate method for management of large ventral hernias with excellent results and minimum complications.

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High-mobility group A2 was recently identified as being upregulated in AT/RT tissue, but the role of HMGA2 in brain tumors remains unknown. Specifically targeting the inflammatory processes may help to reduce this residual risk of major adverse cardiovascular events in atherosclerotic patients. In fresh infarcts, EPO immunoreactivity appeared in vascular endothelium, EPOR in microvessels and neuronal fibers. A rare case of cerebral aspergillus aneurysm at the site of temporary clip application It is yet unclear to what extent Hox target gene selection is dependent upon other regulatory factors and how these interactions might affect target gene activation or repression.

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According to the World Health Organization classification criteria for central nervous system tumors, there were 16 low-grade astrocytomas (2 pilocytic astrocytomas, 14 grade II astrocytomas) and 25 high-grade astrocytomas (5 anaplastic astrocytomas, 20 glioblastomas).The choline/N-acetylaspartate (Cho/NAA) and choline/creatine (Cho/Cr) ratios were calculated. Our results suggested that differentially expressed miRNAs in serum might be involved in ASD molecular pathways, and serum miR-424-5p, miR-197- 5p, miR-328-3p, miR-500a-5p, miR-619-5p, miR-3135a, miR-664a-3p, and miR- 365a-3p might be able to serve as potential biomarkers for ASD because they displayed significant alterations in the expression profile in children diagnosed with ASD. This review examines the recent applications (1995-1999) of soluble polymer supports in the synthesis of combinatorial libraries. A doubtful history of pulmonary emboli or deep venous thrombosis should alert medical personnel to the possible presence of a primary pulmonary artery sarcoma. PH-dependence of detergent-induced hemolysis and vesiculation of erythrocytes.

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Treatment of HepG2 2.2.15 cells with the culture supernatants of PBMCs activated by CpG ODN can remarkably suppress the secretion of HBsAg and HBeAg as compared with that of PBMCs without CpG ODN activation under the same conditions. Six weeks after surgery, the visual acuity had improved from 0.1 to 0.7 and the macular hole was closed.

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Theoretical models were developed to describe the kinetics in HF-LPME, in agreement with the experimental findings. Sorafenib is one of several VEGF-targeting compounds with recently demonstrated substantial anti-tumour effects in metastatic renal cell carcinoma. Single Electrospun PLLA and PCL Polymer Nanofibers: Increased Molecular Orientation with Decreased Fiber Diameter. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma), a member of the nuclear hormone receptor superfamily, plays a critical role in adipocyte differentiation and glucose homeostasis. Generating such datasets is often tedious and introduces subjectivity and interindividual and intraindividual variations.

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After UV irradiation of dominant XP cells, replicative DNA synthesis was depressed to a greater extent than normal and the level of UV induced DNA repair synthesis was lower than that in normal cells. ERK inhibitor PD98059 was found previously to inhibit AP-1 activation by H(2)O(2). To be feasible as a public health strategy, active gaming interventions should achieve more time is spent on active gaming at the expense of non-active gaming. The in planta expression profiles of the oil palm MADS box genes were studied by RT-PCR and phylogenetic sequence diversity within individual subfamilies was investigated by comparing their deduced protein sequences with those of other angiosperms.

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Anacetrapib continued to accumulate in adipose during the treatment period despite apparent plateau in plasma with only minimal decline in adipose levels up to 1 year postdose. A recently described method for analysis of unclassified variants in BRCA1 and BRCA2 provides an extensible framework within which several different types of analytic data can be integrated. The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibrillary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury.

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A study on guided tissue regeneration and tissue engineering-transplantation of collagen membrane seeded with cultured hyaline chondrocytes On the contrary, the analog treatment increased the thermal sensitivity of HA-1 cells, but not of the heat-resistant strains, when these cells were exposed subsequently to elevated temperatures.

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This monitoring system consists of a manometric anorectal balloon and neural electrical stimulation. We excised the ventral urethra because of dribbling complaints up to bulbar area and reconstructed the scrotal transposition, keeping the topic urethra for cosmetic issues. Compared with 0.75mg/kg HgCl2 alone group, BSO pretreatment increased mercury concentrations in the liver, but decreased the concentrations in the renal cortex and urine.

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The Ras-like GTPase Rheb has been identified as a crucial activator of mTORC1. Detailed evaluation of the outcome was conducted in the 89 patients identified as being in class 1 according to the Pesaro classification, in which hepatomegaly, portal fibrosis, and the inadequacy of iron chelation therapy are considered independent risk factors, and the patients are classified as being in class 1 if none of these factors are present, class 2 if one or two of the factors are present, and class 3 if all three factors are present. A post-translational modification of RcaA thus modulates its affinity for DNA. Thus, the pointing shift seen in the previous studies is not from a shifting egocenter location but from a change in the registered position of the eye in the orbit.

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To report the clinical outcome and complications of intravitreal injections of crystalline cortisone in patients undergoing pars plana vitrectomy for treatment of proliferative diabetic retinopathy. High-resolution MRI data at 3 T were obtained from 20 preHD individuals and 20 healthy participants and subsequently analyzed using voxel-based morphometry (VBM), cortical surface modeling and subcortical segmentation analysis techniques. Specific regions of the human occipito-temporal cortex are consistently activated in functional imaging studies of face processing.

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Structure elucidation by one-dimensional and two-dimensional 1H nuclear magnetic resonance and by methylation analysis. However, in genome-reduced bacteria, the limited number of these proteins is insufficient to explain the variety of responses shown upon changes in their environment.

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There was no correlation with the results of the physostigmine test. Plasmid DNA encoding Ag85A provided the strongest protection and showed the least change in lung pathology, followed by plasmid DNAs encoding Ag85B and ESAT-6. In this paper, we provide the basis for a description of structural transitions associated with exposure to low pH and of their role in membrane fusion. In this paper, on the basis of literature review and own experiences, we tried to prove the close relationship between tobacco smoking and occurrence of oral precancers, their malignant transformations and therapeutic effects. It has implications for clinical practice, including the identification of preoperative predictors of outcome and informing appropriate management and rehabilitation of patients.

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Diagnosis of acute vascular rejection (AVR) was made in 19 cases. A healthy human heart rate displays complex fluctuations which share characteristics of physical systems in a critical state. While the toxicity of the stable mutants increased with time, the unstable mutants showed a similar toxicity at early and late time points. Many patients have complained about the quality of care under the HMO regime and limits imposed on them, particularly access to care. Testosterone and lipid peroxide metabolism in orchidectomised rats.

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Lower lipid concentrations with increased creatine kinase were observed with additional simvastatin treatment. To document mood, self-efficacy, and resiliency in people with multiple sclerosis (MS) following a brief group psychological intervention, and to examine whether benefits were greater than those derived from provision of education or group social interaction. Histologically, no evidence of fascia or a rectovaginal septum was identified. EBCT provides anatomic information on coronary atherosclerosis, whereas myocardial perfusion single-photon emission computed tomography assesses the physiologic significance of coronary stenosis. One of the four patients also had hyperuricemia and hyperuricosuria.

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Unplanned Transfers from Hospital Wards to the Neurological Intensive Care Unit. Since the discovery 5 years ago that the D-subunit of succinate dehydrogenase (SDHD) can behave as a classic tumour suppressor, other nuclear-encoded mitochondrial proteins (SDHB, SDHC and fumarate hydratase) have been implicated in tumour susceptibility. The criterion to differentiate IVDs of Pfirrmann Grade I from the other grades is NP homogeneity. Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation. The purpose of this study was to determine the feasibility of using disintegration in an oral syringe for the administration of oral chemotherapeutic tablets.

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As opposed to mitochondria, which generate ROS as a byproduct of their metabolism, NOX enzymes are professional ROS generators. Overproduction of free radicals in combination with cytokines, such as TNF-alpha, IL-6 and IFN-alpha, may result in hepatic cell apoptosis. Because IRF-3 activity is also required for IL-12p70 synthesis, our findings provide a molecular basis for the decreased ability of LPS-stimulated neonatal moDCs to elicit Th1-type responses. Chromoviral diversity in plants, fungi and vertebrates, as shown by phylogenetic analyses, was found to be much greater than previously expected.

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To determine the roles of varroa mites in activating or vectoring viral infections, we performed quantitative comparison of viral infections between bees with and without mites by dot blot analysis and enzyme-linked immunosorbent assay (ELISA). This indicated that the inequality in primary care is likely to be related with the private dominated primary care system in Hong Kong. Adhesive films were doped by spraying an aqueous dispersion of carbon nanotubes (CNTs) over the surface. Chicks were acclimated for 1 wk on a standard grower basal diet. After the parotid tumor had been excised, it was proven histopathologically to be a low-grade mucoepidermoid tumor.

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A first phase of increase is followed by a plateau which occurs before a second phase of increase which can be lethal. Intracellular content of sodium and potassium in patients with hypertension Pandemic planning at the coal face: responsibilities of the public health unit. Invasive carcinoma of both cervices in a patient with uterus didelphys.

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The posaconazole vs fluconazole Management of Penetrating Abdominal Injuries : Comparative Military and Civilian Experiences. Clinical management of infertile men with nonobstructive azoospermia. Aquatic habits appear to have developed very early in turtle evolution.

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Since the signs and symptoms of flucon 150 mg 2 capsulas de vitamina severe infections can be ambiguous, biomarkers provide a more reliable tool in ascertaining the presence of a relevant bacterial infection, its severity and treatment response. Mature data from the ongoing CALGB 90203 and GETUG-12 studies will shed light on this clinical question. Inhibition of Corynebacterium parvum-primed and lipopolysaccharide-induced hepatic necrosis in rats by selective depletion of neutrophils using a monoclonal antibody.

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Cardiac emergencies during pregnancy are rare but gamma synergin injections have significant associated morbidity and mortality when they do occur. Homozygous variegate porphyria: a compound heterozygote with novel mutations in the protoporphyrinogen oxidase gene. This was despite a significant proportion of patients in the IV/IP arms not completing all 6 planned cycles. This compound is the quantitatively dominating eicosanoid in endothelial cells.

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Insulin use was found to be associated with greater bone mineral density loss at the acyclovir 400 mg po bid to iv femoral neck among women with diabetes mellitus. We investigated geographic patterns of herbivory and resource allocation to defense, growth, and reproduction in an invasive biennial, Alliaria petiolata, to test the hypothesis that escape from herbivory in invasive species permits enhanced growth and lower production of defensive chemicals.

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Some amines can achieve very high concentrations and induce a dramatic expansion (vacuolization) of the compartment. We aimed to investigate whether there is a correlation between Modic change and intramedullary high signal equasym depot 30 mg bivirkninger lamotrigin intensity, and to explore the possible risk factors.

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A model of illness self-regulation was used as the theoretical framework for the study. Because there are few cases found in reference material, it seems right to present this problem here. Characterization of two distinct beta2-microglobulin unfolding intermediates that may lead to amyloid fibrils of different morphology. Flow cytometric analysis has shown that the surface marker profile for ASCs is similar to that for BM-MSCs. Effluents metronidazole topical cream 0.75 and acne from three wastewater treatment plants with varying wastewater treatment technologies and design were analyzed for six antibiotics and caffeine on three sampling occasions.

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Here, we describe the isolation and clonal analysis of a mouse bone chibroxin 3 mg ulotka netto marrow progenitor that is specific for monocytes, several macrophage subsets, and resident spleen DCs in vivo. Nitroprusside and prostaglandin E1 completely inhibited the aggregation, mepacrine and imipramine showed marked inhibition while verapamil had only weak inhibition.

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Early diagnosis is difficult and requires a very high degree of suspicion. Molecular characterization of alfuzosin other drugs in same class as nexium two important antifungal proteins isolated by downy mildew infection in non-heading Chinese cabbage. Use of traditional and complementary/alternative medicine (TCAM) in children with cancer in Guatemala.

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From Hymns to Hypotheses: AAAS Black Church Project Brings taking citalopram not depressed but taking Science to Youth. Paradoxical immune reconstitution inflammatory syndrome associated with cryptococcal meningitis in China: a 5-year retrospective cohort study. Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.