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Ciclofosfamida (Cyclophosphamide)

Ciclofosfamida is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Ciclofosfamida is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Ciclofosfamida is in a class of medications called alkylating agents. When Ciclofosfamida is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Ciclofosfamida is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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All the living rats of each group at 22, 28 or 34 weeks were endoscopically inspected for tumor incidence in the colon. Both methods revealed a concentration of the enzyme in osteoblasts and in areas of osteoid that lined the bone trabeculae. Together these experiments indicate that the IKK complex regulates the signal-induced proteolysis of NF-kappaB1 p105 by direct phosphorylation of serine 927 in its PEST domain. Atypical atrial flutter involving the isthmus between the right pulmonary veins and fossa ovalis. The strip was considered failed for a type of vial and storage environment when either control was out of the reference range on a regular testing day and still out of range when tested the subsequent day.

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Possible relationships between problems of affect recognition and other symptoms that characterize schizophrenia are discussed. A 46-year-old man underwent pylorus-preserving pancreatoduodenectomy under the diagnosis of pancreatic tumor. Secondary end points comprise changes in Agatston score, mitral and aortic valve calcification as well as major adverse cardiovascular events (MACE) and all-cause mortality. Aqueous leaves extract showed antibacterial activity against Staphylococcus aureus and Serratia marscesens. The robotic mouse: unravelling the function of AF4 in the cerebellum.

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infantis CGMCC313-2 during or after allergen sensitization suppressed allergic inflammation in lung and intestinal tissues, while the proportion of infiltrating inflammatory cells was significantly decreased in the BALF of allergic asthma mice. Broader inclusion in clinical trials of advanced lung cancer patients with a history of prior cancer should be considered. ETV6 translocation was detected in 10 cases by fluorescence in situ hybridization, whereas intact ETV6 was noted in 2 cases. The results show that the title compound exhibits reversible enol-keto photoisomerization, excellent photostability, and high fatigue resistance. Therefore, it seems that stimulation of SNS by mycobacterial infection or mycobacterium components is a key step in the mechanism of beneficial effects of mycobacterium on MS.

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Scanning tunneling microscopy is employed to investigate the recombinative desorption of H2 from hydrogenated Si(100) surfaces consisting of dihydride (SiH2) and monohydride (SiH) surface species organized in (1 x 1), (3 x 1), and (2 x 1) configurations. The results demonstrate that the mortality for correction of congenital heart defects in children weighing less than 3000 g depends on several factors. A 0.3 mg/kg dose of ketamine given at approximately 5 min before surgery resulted in decreasing the number of times pressing the PCA and the administration of additional analgesics. The patient could consequently benefit from treatment, i.e., radiation therapy, which was followed by clinical relief.

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The study aimed to systematically appraise the evidence on the effects of low level laser therapy (LLLT) on bone healing following rapid maxillary expansion (RME). Histoenzymological changes, indicating inhibition of the main metabolic processes, were found in the conduction cardiomyocytes of the left ventricle and ventricular septum in experimental stenosis of the aorta. Cell 9, 3031-3040, 1998) in which the 30 nm chromatin fiber of each chromosome forms a string of loop clusters (micelles).

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Molecular inhibitory mechanism of dihydromyricetin on mushroom tyrosinase. Immunohistochemically the hepatic glucokinase protein is detected in the perivenous area.

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The study confirms that Apo-A level is highly related to the degree of liver injury and also suggests that this decrease may be mainly due to impaired liver synthesis and that the serum levels of Apo-A and Apo-B can be utilized in the differential diagnosis of chronic liver diseases. Macromolecular assembly analyzed by converging structural techniques. Effect of trimethoprim/sulfamethoxazole on thyroid function in dogs with pyoderma. Risk factors for the development of well leg compartment syndrome after sex reassignment surgery in patients with gender identity disorder.

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Secreted production of a custom-designed, highly hydrophilic gelatin in Pichia pastoris. Acupuncture and Trager are both effective treatments for reducing chronic shoulder pain associated with functional activities in persons with SCI. Odorant-sensitive adenylate cyclase may mediate olfactory reception. Previous speculations that the oncogenic mechanisms underlying asbestos and erionite carcinogenesis may differ led us to examine whether the p53 gene is targeted in erionite carcinogenesis. Cardiovascular diseases associated with HIV infection and their management.

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Ciliated cells appeared to be the primary target of this strain of influenza virus and demonstrated the greatest degree of damage. However, other pathways may also contribute to these responses, including those that dually participate in motor control and regulation of sympathetic nervous system activity. Potential role of pemetrexed in metastatic breast cancer patients pre-treated with anthracycline or taxane.

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Recent trends in the diagnosis and management of allergic rhinitis. Such was the case in our patient who had anal pinworms (Enterobius vermicularis). Transpulmonary pressures and lung mechanics with glossopharyngeal insufflation and exsufflation beyond normal lung volumes in competitive breath-hold divers. The histopathology, imaging, and treatment of three unique cases of head and neck inflammatory pseudotumors are described in this case series.

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The enzyme was resistant to degradation by proteases that are normally present in the intestine, a site inhabited by the Eimeria parasites, and it was relatively resistant to heat, with optimum activity being at 40 degrees C, which is within the range of temperature in the chicken intestine (40-43 degrees C). Gastroesophageal reflux and laryngeal cancer: causation or association? Persistence of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte clones in a subject with rapid disease progression.

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Although the importance of atomic motion to how proteins function has been conjectured for several decades, the characterization of protein dynamics on multiple time scales is scant. Investigations toward enhanced understanding of hepatic idiosyncratic drug reactions.

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The purpose of this study was to characterize and compare the interfacial chemistry of adhesive with caries-affected and noncarious dentin using micro-Raman spectroscopy. Quality of life after adenotonsillectomy in children with obstructive sleep apnea: short-term and long-term results.

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Treatment of acromegaly with a long-acting synthetic analog of somatostatin The literature describes women throughout the world experiencing degrees of sadness postnatally, which persist up to 1 year. In this review, we describe the existing approaches for delivery of brain-derived neurotrophic factor (BDNF), which is the most abundant neurotrophin in the mammalian central nervous system (CNS). The lack of invasion effects on most soil properties does not necessarily imply the lack of influence of invasive plants, but may suggest that the direction of the changes varies among replicate sites and there are no general patterns of invasion-induced alterations for these parameters.

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Prenatal influence of ischemia-hypoxia-induced intrauterine growth retardation on brain development and behavioral activity in rats. The transplanted tumors infiltrated the liver and spleen, and leukemic megakaryoblastic cells appeared in the blood of some transplanted mice. Mobile monitoring with a Scintrex LMA-3 luminal monitor was used on a neighborhood scale to measure the NO2 concentration at sites that covered a large geographical area. Among the different mammalian isoforms of Carbonic Anhydrase, the hCA VII is mainly expressed in the brain where it is involved in several neurological diseases. Causality links among renewable energy consumption, CO2 emissions, and economic growth in Africa: evidence from a panel ARDL-PMG approach.

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