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Orlica (Orlistat)
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Orlistat

Orlica was approved as a prescription product by FDA in 1999 for obesity management in conjunction with a reduced caloric diet, and to reduce the risk of regaining weight after prior weight loss. In 2007, Alli (Orlica 60mg) was approved for OTC use for weight loss in overweight adults, 18 years and older, in conjunction with a reduced-calorie and low-fat diet.

Other names for this medication:
Orlistat, Cobese, Ishape, Lipocut, Lipophage, Obelit, Obezita, Oristal, Orlica, Reeshape, Vyfat, Xenical,

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These results provide the first evidence for the potential use of FTY720 as a therapeutic agent in a variety of B-cell malignancies, including CLL. We present a male infant, born at term, who collapsed and died at 30 minutes of age. In the absence of IL-7 normal pre-B cells differentiate to VHDHJH/VLJL-rearranged, surface immunoglobulin-positive B cells expressing the alpha chain of the IL-2 receptor. In an intraperitoneal model of ovarian cancer, FGF2-Ad generates increased transgene expression in tumor tissue when compared with Ad.

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A canine abdominal aortic aneurysm model of type II endoleak with an implanted pressure transducer was used to evaluate the use of polyurethane foam to induce thrombosis of type II endoleaks. GLN administration at levels similar to or higher than physiologic concentrations decreased IL-8 and CAM expressions, and PMN transmigration decreased after stimulation with preeclamptic plasma.

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Further analyses showed that men in the experimental group rated a significantly heavier female body size as maximally attractive than the control group. The protein cores of all three proteins were confirmed to be bikunin by mass spectrometry and Western blot.

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Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain. Due to this simultaneity, ionic shifts created by traumatic influences are avoided even in the outermost cells of the specimen. Clinical efficacy of OM-85 BV in COPD and chronic bronchitis: a systematic review.

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EphB4 knockdown through EphB4 shRNA inhibited EPO-mediated osteoblastic phenotypes. There is, however, an overall negative relationship between alcohol consumption and technical aspects of work performance as indicated by workplace collateral reports. Lymphatic complications like lymphcysts and -fistulas are harmless in most cases and regress spontaneously. Although it has long been speculated that this defect was caused by an abnormality at the site of the nuclear receptor for thyroid hormone, isolation of complementary DNA encoding thyroid hormone receptors has only recently enabled us to directly examine this hypothesis. Dinucleotide repeat polymorphism near the RP3 locus in Xp21 (DXS1110).

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An unexpected PtCl4-catalyzed cyclization reaction of tertiary indol-2-yl-3-alkynols occurred smoothly in toluene to form various poly-substituted carbazole derivatives efficiently. Immunological methods and proteomic were used to detect and to characterize BSDL in urine. A familial history of ovarian cancer/breast cancer is considered a significant prognostic factor for ovarian cancer. Four experiments were performed: In experiment 1, the original selective breeding of rats for apomorphine susceptibility (leading to APO-SUS and APO-UNSUS rats) was extended and replicated in an independent group of Wistar rats.

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The ability to fabricate multiple devices using injection molding or hot-embossing techniques of polymers provides a lower cost alternative to silica-based devices currently utilized with mass spectrometry. Paralytic shellfish poisoning: a potential public health problem. The data presented herein suggest that the biogenesis of complex I is linked with its assembly into supercomplexes. Indeed, residual dipolar couplings and the structure calculations indicate that the relative orientation of the two domains is not rigidly oriented with respect to one another in solution. There were significant decreases in the anterior cingulate cortex, bilateral hippocampi, cerebellums, and right insula of patients with schizophrenia, compared with healthy subjects.

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The different findings regarding the presence of apoptotic cells suggest a contribution of pathobiological pathways in the patients with DM to the underlying heart disease. We recorded the activity of 11 ELMs and 5 ILMs during coughing in which ELMs, but not ILMs, exhibited increased membrane depolarization and discharge frequencies.

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PYR/PYL/RCAR proteins are putative abscisic acid (ABA) receptors that play important roles in plant responses to biotic and abiotic stresses. These findings suggest that orexin A affects sympathetic activity, which controls body temperature. The purpose of this study was to investigate whether these activities are expressed in the slime mold Physarum polycephalum in which all the nuclei traverse the cell cycle in natural synchrony.

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Comparative analysis of the phosphoproteome also yielded new functional information on proteins controlled by redox regulation (thioredoxin target proteins) and proteins of the chloroplast 70S ribosome, the centriole, and especially the flagella, for which 32 phosphoproteins were identified. Implementation of school based physical activity interventions: a systematic review. Gill-raker counts did not commensurate with hierarchical mtDNA clades, and poorly with haplotypes, suggesting recent origin of gill-raker variation.

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Altered differentiation of neural stem cells in fragile X syndrome. To examine the role of glia-derived S100beta protein and to evaluate its use as a biochemical marker in childhood acute recurrent headache. The metal model simulating abutment preparations had triangle-formed circular needles on the surface. In the future with the move to outcome based block funding, it will be important for projects to adopt broader target groups, refine and develop interventions and develop greater sustainability through responding to local needs, improving design and evaluation and ongoing funding.

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We describe the use of lymphatic mapping and sentinel lymph node biopsy in a patient after basal cell carcinoma was identified within a lymphatic vessel in the primary excisional specimen. Signal transduction pathways in cancer development and as targets for cancer prevention.

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Advice is given on the use of clinical impressions and functional characteristics to determine the level of hypothermia. Draining lymph node uptake was influenced by both the intracavitary radioactivity retention level and metastasis status. Crucial to the behaviour of this hydrogel is the serendipitous discovery of cofacial nanosheet alignment in aqueous colloidal dispersions subjected to a strong magnetic field, which maximizes electrostatic repulsion and thereby induces a quasi-crystalline structural ordering over macroscopic length scales and with uniformly large face-to-face nanosheet separation. Mac-1(-/-) PMNs were unable to spread on Ab-opsonized target cells and other Ab-coated surfaces. These results did not demonstrate any statistically significant GGE-induced changes in the EEG.

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Extreme tooth enlargement in a new Late Cretaceous rhabdodontid dinosaur from Southern France. Correlation Filters for Detection of Cellular Nuclei in Histopathology Images. Modulation of morphological differentiation of human endothelial cells in culture by the synthetic peptide YIGSR and cytochalasin B. A family history of breast cancer had little effect on the risk in women with nonproliferative lesions. However, the amount of liver parenchyma related to it can vary from person to person.

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Patients who survive the first year after cardiac Tx can be bridged by VAD to ReTx with an expectation that outcomes can be similar to ReTx patients who did not require MCS. Evidently the videotaped instruction was sufficient to allow both groups to improve in performance of the power clean. To be published in the next issue of the Scandinavian Journal of Rheumatology. In addition, DNA was available for PCR (open reading frame 26 (ORF 26), ORF 72, ORF 75) in three patients (two without AIDS, one with AIDS).

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Moreover, the phosphorylation of ATG4B at Ser34 enhanced its mitochondrial location and the subsequent colocalization with F1Fo-ATP synthase in HCC cells. Antifibrinolytic agents in cardiac surgery: current controversies. Using a plasmid assay, we previously demonstrated that repair in Escherichia coli generated a double strand break (DSB) from two closely opposed uracils when uracil DNA glycosylase initiated repair.

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The relevant physical phenomena that dominate electrophoretic transport of ions and macromolecules within long, thin nanochannels are reviewed, and a few papers relevant to the discussion are cited. We examined animals lacking brain-derived neurotrophic factor (BDNF) in order to establish whether this neurotrophin could be involved in the generation and/or survival of these neurons in vivo. During Time Period A, women underwent cervical ripening at 19:00 hours and were reviewed the next morning for amniotomy and oxytocin infusion (ARM/oxytocin). Taken together, our findings reveal a novel molecular function of WDR79 and may lead to broadly applicable and innovative therapeutic avenues for NSCLC. Provided care is taken during the fibre-optic visualization of the duodenal bulb, the endoscopic appearances of moderately severe duodenitis correlate well with the histological changes seen.

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To clarify this question we have investigated the molecular arrangement in mineralized and unmineralized turkey leg tendon as a model for the collagen of mineralized tissues. Phylogenomics solves a long-standing evolutionary puzzle in the ciliate world: The subclass Peritrichia is monophyletic. Bone age assessment with conventional ultrasonography in healthy infants from 1 to 24 months of age. In one mutant (strain G29), the proportion of the phospholipids separated by TLC was different from the parental strain.

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Exactly which of the above two processes, or possible combinations thereof, is responsible for the present finding is not known. These results demonstrate the difference between the fore- and hindlimb buds in the cell competence of Shh induction in response to FGF-4, suggesting the possibility that the responsiveness of mesenchymal cells in signaling molecules is not the same in the fore- and hindlimb buds. Spread GATA-1 platelets bound very few vWF multimers, which were much smaller in size than those on normal spread cells, but were able to move then to cell centers.

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The Oregon brain aging study: neuropathology accompanying healthy aging in the oldest old. Papers were included if they described randomized controlled trials (RCTs) on humans and if the primary aim was wound closure, with a secondary aim of measuring wound healing over time.

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The purpose of this study was to evaluate whether deeper-than-recommended insertion of a suture anchor within the rotator cuff footprint of human cadaveric humeri affects fixation characteristics. Heat shock transcription factors (HSFs) and heat shock proteins (HSPs) play important roles in enhancing thermotolerance of plants. It has been reported that during Drosophila embryonic development, and in cell culture, that the Rac GTPases are redundant.

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The above quantities are rarely presented when scientists make statements about the potential usefulness of a risk factor or genetic marker in screening for future disease risk. Immunohistochemical stains showed that the tumor cells lacked expression of keratin, S-100 protein, desmin and CD34. Such assays accelerate RNA structure analysis and provide researchers with new technologies to tackle biological questions on a transcriptome-wide scale. The environmental contribution (endogenous or exogenous) is much more pronounced in the common forms of migraine, with the identification of numerous predisposing or triggering factors, among which only some can be avoided. Treatment with resistin significantly attenuated Dox-induced apoptosis in a dose- and time-dependent manner, resulting in an increase in breast cancer cells survival.

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The aim of this systematic review and meta-analysis was to compare the role of FDG-positron emission tomography (PET) or PET/computed tomography (CT) with conventional imaging in the detection of primary and nodal disease in anal cancer, and to assess the impact of PET or PET/CT on the management of anal cancer. The 3D alginate hydrogels system has previously been shown to potentially promote chondrogenesis. Both implant variants did not inhibit osteoclast differentiation.

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Urine albumin excretion measured over consecutive weekends and on repeated first morning collections from normal children showed considerable variation both during the day and from day to day in each subject. Two ultramarathon runners were hospitalized with hyponatremic encephalopathy after completing 80 and 100 km (50 and 62 miles), respectively, of the 1983 American Medical Joggers Association ultramarathon race in Chicago. Characterization of the detachable Rho-dependent transcription terminator of the fimE gene in Escherichia coli K-12. Evaluation of an enzyme immunoassay system for measuring herpes simplex virus (HSV) type 1-specific and HSV type 2-specific IgG antibodies. Management of gestational diabetes: pharmacologic treatment options and glycemic control.

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Prognosis of proliferative lupus nephritis subsets in the Louvain Lupus Nephritis inception Cohort. Bryodin, a single-chain ribosome-inactivating protein, selectively inhibits the growth of HIV-1-infected cells and reduces HIV-1 production. For example, certain NSAID derivatives have been identified that do not inhibit COX-2 but have demonstrated efficacy to suppress carcinogenesis with potential for reduced toxicity. Recently, inertial sensors have been used to measure human movements for the purpose of rehabilitation.

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Continuous stimulation of transected distal nerves fails to prolong action potential propagation. Our preliminary data suggest that this surgical technique results in improvement in pain, range of motion, and function.

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Correlation of DNA sequence specificity of anthramycin and tomaymycin with reaction kinetics and bending of DNA. Ultrastructural observations in an alcoholic patient with post-surgical pseudomonas infection.

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Postoperative infusion of local anesthetic around the lumbar plexus reduces morphine requirement and improves early recovery after total knee arthroplasty as compared with a single-injection block. Physical independence and occupation were the most severely affected domains on the LHS. Electrodiagnostic criteria for carpal tunnel syndrome in axonal polyneuropathy. These findings suggest that by following word-by-word incremental production, speakers with PD compromise fluency and accuracy of speech to a greater extent than healthy older speakers and that PD is associated with impaired inhibitory control during lexical selection.

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We report here the behavior of a class of nonchemotactic mutants (cheX) that can carry out sensory excitation but are defective in the process of sensory adaptation. Everyday police work during mental health encounters: A study of call resolutions in Chicago and their implications for diversion. The adhesability and behaviour of ceramic facings of telescoping adhesive elements from baked alloys were tested in prolonged experiments. Such sources are identified to mostly originate from within a sample of five developed countries.

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The acute toxicity and growth inhibiting effects were destroyed by heat during the drying of the fruits. A possible relationship between moisture and tight junction formation was further suggested by organ culture experiments during which brief incubations stimulated an increase in the number of junctional strands and diminished numbers of lamellar bodies. Radioactive chromium accumulated in human erythrocytes exists in two forms: one bound to macromolecules, e.g., hemoglobin, and one in a low molecular weight form. Aortic atherosclerosis at middle age predicts cerebral white matter lesions in the elderly. Chylous ascites following operation for para-aortic lymph node dissection in a patient with cervical cancer.

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military has changed markedly over the course of 20th- and 21st-century conflicts. The duration of anesthetic effect and the histopathologic changes resulting from a controlled freeze of the palmar and plantar digital nerves in the horse were evaluated. Efficacy of VDT PACE-like regimens in treatment of relapsed/refractory multiple myeloma. Single-channel and whole cell currents were measured in transfected tsA201 cells and in Xenopus oocytes respectively.

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In each patient, arterial phase and venous phase volumetric data sets were acquired after the intravenous injection of 150 cc of non-ionic contrast material. However, the microphysical mechanisms responsible for the transition from ductile flow to seismogenic brittle/frictional behaviour at shallower depths remain unclear.

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The cost of anticholinergic may be responsible for both early discontinuation of treatment and incomplete adherence to therapy with unsatisfactory results on symptoms and an incorrect assessment of the effectiveness of the drug by the urologist. We find that activation of IRF7 results in the induction of MAP3K8 and restructuring of the antiviral transcriptome. Two outer membrane proteins contribute to cellular fitness in Caulobacter crescentus by preventing intracellular S-layer protein accumulation.

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Four weeks after TAC, both the heart weight/body weight ratio and the lung weight/body weight ratio were lower in the voglibose group than in the TAC group. This mutant may be useful for research that would contribute to the elucidation of genetic mechanisms controlling the process of spermatogenesis and as a model animal for male infertility in humans.

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Edwin Hartley Pratt and orificial surgery: unorthodox surgical practice in nineteenth century United States. Levamisole is a drug which enhances defective cellular immune responses. Individual giant fibers terminate primarily on pectoral fin motoneurons contralateral to their cell bodies, but may also send a branch back across the midline to ipsilateral motoneurons.

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A hydroponic rice seedling culture model system for investigating proteome of salt stress in rice leaf. Does oedema following lower limb revascularisation cause compartment syndromes?

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A new model of arterial thrombosis in rats was based on a combination of a localizing hemodynamic factor /partial mechanical constriction of aorta/, generalized clavomed o augmentin and breastfeeding mild endothelial lesion /i.v.hypotonic saline/ and a humoral factor/i.v. This solves the problems of low bioavailability, uncertain dosage and uneven surface distribution which are commonly seen when petrolatum is used as the vehicle. Concurrent chemoradiotherapy in the management of squamous cell cancer of the oropharynx: current standards and future directions.

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Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats. Professional safety representatives were assigned to every department, information and diffusion sessions were held, and a new incident reporting system was implemented. A clear picture of intestinal obstruction only unfolded terminally. We studied whether acute PVR (adenosine and waiting time) and late PVR (at repeat) are explained by incomplete transmurality and contiguity within the deployed radiofrequency circle. Satellites can monitor various hydrological phenomena, including regional and global algia pharmaceuticals industry snow cover, river and sea ice extent, and areas of global inundation.

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The obstetric consultant on the labour ward: beyond infancy to early adolescence. In Experiment 2, transfer performance was investigated for categories fexofenadine dose for allergy varying in size (5, 10, 20), partially crossed with the number of exception patterns (1, 2, 4). Bone-anchored intermaxillary elastics in an asymmetric Class II malocclusion: A case report. Our results provide insight into the mechanism of osteoarthritis by showing that loss of Mig-6 leads to early onset of this disease, implying that this gene or its pathway is important in normal joint maintenance.

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The present study is the first to confirm the distribution of A. Iodine-131 radio-guided surgery in differentiated thyroid cancer: outcome on 31 patients and review of the literature. In this review, we discuss these issues and summarize recent pantoprazole sodium tab developments concerning this non-MHC-dependent regulation of NK cell function.

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Elastic resistance of the spine: Why denoral toothpaste for dinner does motion preservation surgery almost fail? Yeast RAD4, its human ortholog Xp-C and their orthologs in other eukaryotes are DNA repair proteins which participate in nucleotide excision repair through a ubiquitin-dependent process.

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