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Endoxana (Cyclophosphamide)
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Cyclophosphamide

Endoxana is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Endoxana is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Endoxana is in a class of medications called alkylating agents. When Endoxana is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Endoxana is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Influence of recombinant bovine cytokines on proliferation of a bovine mammary epithelial cell line. Developing emergency care systems and task sharing aspects of acute surgical care addresses many of these issues. Hydrogel did not allow the majority of cells to adhere well but maintained their viability. The surface pattern can also be generated as negative form from a CT data set using a computer-assisted design/manufacture system.

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Several putative determinants and candidate effectors responsive to Agrobacterium mediated transformation of wheat cells were discussed. Renal function is an important prognostic factor in heart failure. This is important in the design of clinical cancer treatment protocols.

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Delayed Open Reduction and K-Wire Fixation of Widely Displaced Supracondylar Fractures of Humerus in Children using Medial Approach. Properties of LAK cell activity and LAK-generation in PBL isolated from patients with renal cell carcinoma Classic Period collapse of the Central Maya Lowlands: insights about human-environment relationships for sustainability. The responses (text comments) were analysed using content analysis with analyst triangulation.

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The half-life of the proteins in the extracellular space varied between 15 min and 2 h. Human T-lymphocytes activated by phytohemagglutin acquire insulin receptors in culture. The DNA binding site for each of these proteins contains identical nucleotide triplets (CGG ... Analysis of slc19a2, on 1q23.3 encoding a thiamine transporter as a candidate gene for type 2 diabetes mellitus in pima indians. Bacteriorhodopsin (BR) is a membrane protein which pumps protons through the plasma membrane.

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Seasonal variation of Zn, Pb, Cu and Cd concentrations in the root-sediment system of Spartina maritima and Halimione portulacoides from Tagus estuary salt marshes. Supervision of the postoperative period in biliary shunt operations: validity of sequential hepato-biliary scintiphotography with 99mTc-HIDA To some extent, this may have occurred with regard to the treatment of hypertension, especially concerning the use of diuretics and beta blockers and the significance of their metabolic effects. Carbapenems are first-line agents for the treatment of serious nosocomial infections caused by multidrug-resistant Enterobacteriaceae. Saliva from parotid and submaxillary-sublingual glands contained similar quantities of the serum proteins, whereas more ABO and Lewis blood group substances were found in saliva from submaxillary-sublingual glands than in that from parotid gland.

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Homogalacturonan pectin domains are synthesized in a highly methyl-esterified form that later can be differentially demethyl esterified by pectin methyl esterase (PME) to strengthen or loosen plant cell walls that contain pectin, including seed coat mucilage, a specialized secondary cell wall of seed coat epidermal cells. Changes in MCAv appear to depend on the pacing strategy adopted, with a positive pacing strategy likely to contribute to a hyperventilatory drop in PetCO2 and subsequent reduction in MCAv.

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Therefore, our study suggested that the miR-193b-3p/PAK3 axis might be a potential novel therapeutic target for OC. Women with pathologically elevated prolactin secretion (hyperprolactinemia) were found to have lower serum hepcidin compared to those with normal prolactin levels, without showing significant difference in other hepcidin-regulating factors. We postulate that the missing protein isoform arose due to the lack of a PTM. Nevertheless, different wing sections dominate the New versus Old World clines.

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Semi-quantitative evaluation of LV regional wall motion showed abnormal contraction of the anterolateral walls. A systematic study of the system capabilities as a portable instrument was performed to optimize range, sensitivity, short term and long term stability, dynamic behaviour, effect of temperature and humidity, and temporal drift. However, recent studies showing that exposure to ionising radiation results in elevated mutation rates detectable in the non-irradiated progeny of exposed cells challenge the existing paradigm in radiation biology. Comparisons between theory and experiment have used Tanabe-Sugano energy level diagrams for determining the symmetries and relative energies of intra-d-state transitions for an equivalent d2 ground state occupancy. These results suggest a second mechanism of absorption may be induced during a dietary zinc depletion that is carrier mediated.

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The aim of the present investigations was to test the involvement of the glutamatergic innervation of the hypothalamic paraventricular nucleus in the prolactin response to stress. This has important implications for future health promotion interventions designed for general practice. Trabecular plate thinning can be observed and perforations occur on very thin plates in CSIOP patients. About them, hemoglobin, platelet, C-reactive protein, rheumatoid factor, total cholesterol, triglyceride, duration of disease, functional class, and dose of steroids per day were measured. An occlusal analysis should be performed in patients exhibiting TMD symptoms to identify the presence or absence of any discrepancy between the HOP and the BPOP.

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The effective number of bacterial species and bacterial distribution patterns were compared with those known for communities of cactophilic yeasts. In the UDP all examinations, performed by the GP, follow standardized procedures, results being sent to the diabetologist. Unattended continuous infusion of fentanyl for postoperative pain management. The structure, exhibiting a guanidine moiety acylated by two terpenoid acid units, has been established by spectroscopic methods and secured by synthesis.

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MEDLINE, Embase and the Cochrane Central Register of Controlled Trials were searched by two independent authors. The present data provide direct evidence for the inference from imaging of bidirectional wave motion that the stimulus-induced electrical waves in turtle visual cortex correspond to phase shifts in a network of coupled neuronal oscillators. Analyses of unstimulated and stimulated suspension cultures indicate that activities known to influence megakaryocyte development in vitro also increase total megakaryocyte antigenic content. Noxious stimulation significantly altered EMG responses but only in full trunk flexion.

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Although in vitro studies have shown that Nd:YAG laser irradiation results in a reduction of enamel mineral loss after acid challenge, this hypothesis has not been tested using an in situ caries model. Here, we review the genomic organization, evolution, and transcriptional regulation of the multigene family of intracellular lipid-binding protein (iLBP) genes from teleost fishes. The finding that chromosome evolution is not a uniform process in sedges provides a novel example of karyotypic orthoselection in an organism with holocentric chromosomes.

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Blood samples were obtained before and 20, 60, 80, and 120 minutes after the beginning of the test. A method for assessing responses of small arteries in man: effect of physiological and pharmacological stimuli. Effectiveness of commercial video gaming on fine motor control in chronic stroke within community-level rehabilitation. A prospective, randomised trial of the Ambu AuraGain laryngeal mask versus the LMA Protector Airway in paralysed, anaesthetised adult men.

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ClinicalTrials.gov Identifier: NCT02132039 , registered on 28 April 2014. However, using perlite alone had negative effects on the skin, the moisture percentage of bedding and stress parameters. Equol, a Clinically Important Metabolite, Inhibits the Development and Pathogenicity of Magnaporthe oryzae, the Causal Agent of Rice Blast Disease. One hundred and fifty organisms, comprising bacteria, fungi and actinomycetes, were isolated from straw-compost, manure, soil, drainage material and soil enriched with virus concentrates, and were tested for antiviral activity in vitro. A dose-finding study of azithromycin in the treatment of acne vulgaris.

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Recent research has established that sterol regulatory element binding protein-1 is a critical intermediate in the pro- or anti-lipogenic action of several hormones and nutrients. Cavernous artery obstruction following blunt trauma to the penis. Effect of BANS location on the prognosis of clinical stage I melanoma: new data and meta-analysis. Increasing prevalence of Plasmodium vivax among febrile patients in Nouakchott, Mauritania.

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A systematic search was conducted in six databases for articles providing data on HIV-positivity, protease inhibitor exposure, and GDM or glucose intolerance development in pregnancy. There are many more examples of such effects, including the following which are discussed in detail: 1. Moreover, we found that levels of PAX3 and MET were positively correlated in matched human GC specimens, and their coexpression was associated with poor prognoses.

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Cisplatin/etoposide is a highly active regimen in metastatic breast cancer, but cisplatin dose-escalation is limited by nonhematologic toxicity. Using a luciferase reporter gene and green fluorescent protein reporter gene, we demonstrate that A3G and other APOBEC family members can counteract the inhibition of protein synthesis by various microRNAs (miRNAs) such as mir-10b, mir-16, mir-25, and let-7a. Although centrioles, cilia and flagella have cold-stable microtubules, MAP6 proteins have not been identified in these organelles, suggesting that additional proteins support this role in these structures.

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Firstly, the sperm motility pattern of cryopreserved semen was evaluated after thawing by means of both visual and computer-assisted analyses. introduces new childhood vaccines and policies that may change the timing of existing vaccines. When these goals are met, noninvasive NPPV can offer patients greater comfort, simpler and more convenient ventilator use, and reduced rates of infections, complications, and hospitalizations as compared with tracheostomy IPPV. Dominance in male chimpanzees has very real benefits as high-ranking males have priority access to resources and potential mates, and father more offspring than do low-ranking conspecifics. Prosthodontic restoration in edentulous patients who have undergone hemisection of the mandible is difficult because of the instability of the mandible after resection and the lack of teeth necessary for successful retention of a guidance appliance.

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Aspects of the Warburg effect are analyzed in the context of the established hallmarks of cancer including the role of oncogenes and tumor suppressor genes. Many of these lesions abut the great vessels and limit the length of the proximal landing zone.

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We describe the improved ability to catheterize the distal splenic artery consistently using a flexible, flow-directed, 5-F, Swan-Ganz catheter so as to embolize the spleen beyond any pancreatic branch origins to achieve the safe treatment of hypersplenism. Structure and synthesis of a lipid-containing bacteriophage: in vitro protein synthesis directed by bacteriophage PM2. Morbidity and mortality follow this spatial pattern, which is usually attributed to these pollutants. Permanent ketosis is a pathognomonic characteristic of SCOT-deficient patients with severe genotype. Rarely systemic complications like acute renal failure can occur following multiple stings.

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Sequential evaluation of hepatic functional reserve by 99mTechnetium-galactosyl human serum albumin scintigraphy after proton beam therapy: a report of three cases and a review of the literatures. We report a case illustrating the successful non-surgical management of an arteriovenous fistula resulting from central line placement. epidermidis biofilm formation is reviewed and current thinking on the relevance of these mechanisms for S.

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Sunflower sesquiterpene lactone models induce Orobanche cumana seed germination. Borderline Personality Disorder and Religion: A perspective from a Muslim country. Major complications occur rarely after mesial temporal surgery on epileptic patients. Apart from accurate modelling of the resected segment using a template, the key features of the technique include firm fixation and wrapping the plate with pectoralis major muscle.

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These data suggest that the influence of Cd on testicular gene expression involves a specific effect on the LH receptor and not a general effect on seven-transmembrane-spanning receptors. Glu144, Tyr158, and His228 of BANP were located near the active site Zn ion, to which three amino acid residues, His143, His147, and Glu167, were coordinated.

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The bone marrow findings did not associate with the severity of skeletal phenotype. Effect of sample dilutions on arterial blood gas determinations. We report (129)Xe NMR experiments showing that a Fe4L6 metallosupramolecular cage can encapsulate xenon in water with a binding constant of 16 M(-1).

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Genomic suppression of murine B29/Ig-beta promoter-driven transgenes. Injury to a specific neural pathway detected by ultra-high-field MRI. These findings suggest that ADPC-PRP therapy should be considered for dogs with ST. The objective of the current study was to characterize within-stage migration of tumor size in breast carcinoma, and to estimate the effect of this shift on reported breast carcinoma survival.

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The interaction between volatile anesthetics and the immune system is discussed in the context of pathogenesis of infectious disease. The major complication of VICC is hemorrhage, including intracranial hemorrhage which is often fatal. Semen intake, on average, was complete between four and eight minutes with the majority of gilts and between four and seven minutes with most of the old sows, but no evidence was obtained as to any action of the oxytoxin upon intake intensity. Furthermore, two-hybrid experiments indicated that Ptr3p interacts with Ssy5p and that Ptr3p can self-associate. Expression of p57 and homeobox A10 during decidualization of endometrial stromal cell in vitro.

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In most bacteriophages of gram-negative bacteria, the phage endolysin is released to its murein substrate through a lesion in the inner membrane. The subjects were given two grades of exercise each lasting for about five minutes with a rest of fifteen minutes in between on a mechanically braked bicycle ergometer.

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The fiber-reinforced and nanohybrid composite resin had higher values in the short-post technique, and there was no significant difference between the different fiber posts. We have identified HSF1 as the mediator of stress-induced heat shock gene transcription.

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The structures of 1-5 were elucidated by spectroscopic methods and through comparison with data reported in the literature. Brain concentrations of tyrosine and the other amino acids measured were unaltered. These results suggest that CO and CO2 enter and exit the enzyme at the water channel along the betabeta subunit interface.

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Abnormal ocular motility with brainstem and cerebellar disorders. Providing effective intervention to manage exacerbation requires an understanding of the issues that are faced by patients and their carers. The AT cell fails to pause sufficiently after X-ray or similar radiomimetic insults to repair damage. Surgical treatment of necrotizing enterocolitis: suspicions and dilemmas

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The purpose of this study is to demonstrate the rational design and behaviour of the first dual-mode optical and chemical prodrug, exemplified by an acetyl salicylic acid-based system. An improved classification of neurocysticercosis (NCC) that delineates active from inactive forms of the disease will eventually be important in the research of immunodiagnosis and in therapeutic trials.

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Appreciable protection from stroke in later life is conferred by vigorous exercise in early adulthood. The disproportionate burden of diabetes in African-American and Hispanic populations. Osteoporosis in Rheumatoid Arthritis: role of the vitamin D/parathyroid hormone system A 4-week, lifestyle-integrated, home-based exercise training programme elicits improvements in physical function and lean mass in older men and women: a pilot study.

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No complications, such as a deterioration of hearing due to inner ear damage or a conductive hearing loss, were observed in the long-term. Basal, insulin (100 nmol/L)-, and sorbitol (250 mmol/L)-stimulated glucose uptake levels were measured. Beyond biomedicine: the challenge of teaching preventive medicine.

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The polydioxanone clips were found to be superior to the metallic clips in ease of clip loading to the applier, security of clips in the transfer to the surgeon and security of the clip in the applier when positioning to ligate vessels. However, the customer is provided less inner details about changes in the new software version. Building Blocks of Psychology: on Remaking the Unkept Promises of Early Schools. In 50 patients, brain metastasis was verified pathologically and some case data were available, including the five reported here.

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Cerebral microhemorrhages (CMHs) are associated with rupture of small intracerebral vessels and are thought to progressively impair neuronal function. These results add to a growing body of evidence which demonstrates the existence of widespread nonmotor cortical input to the basal ganglia, and an organization of this input far greater in complexity than that demonstrated by earlier suppressive silver impregnation methods. Direct evidence of monohydrogen phosphate in a (1)H NMR spectrum of unmodified bone is presented for the first time. Both mechanisms are controllable, thus, do not necessarily preclude the use of polyether polyurethanes in implantable devices. Mitral valve prolapse can be diagnosed by echocardiography or by auscultation where a characteristic mid-systolic click and late systolic murmur can be heard.

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Balancing Our Perceptions of the Efficacy of Success-Based Feedback Manipulations on Motor Learning. Sixty-three consecutive patients with AMI were divided into two groups according to the timing of PCI, namely direct PCI and lamictal reviews ask patient zantac indirect PCI groups. Pseudoxanthoma elasticum-like phenotype with cutis laxa and multiple coagulation factor deficiency represents a separate genetic entity.

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Preduodenal Portal Vein: A Rare Cause of Neonatal Bowel Obstruction. Among one peer group of isosexually reared males, their level of sexual competence conformed with their nizagara doses dominance ranks when immature.

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Protein biosynthesis and thyroglobulin polyribosome content of thyroid cells in congenital goiter This leads to the belmazol 20 mg posologie metronidazole disassembly of the stress fibers and the observed fluidization. Exposure of the alimentary canal of these vectors to the host immune effectors necessitates efficient counteractive measures by hematophagous vectors. The difficulty of establishing structure-activity relationships in the beta-lactam family of antibiotics stems from the fact that: (1) The targets in various bacteria exhibit widely different sensitivities. When end-tidal PCO2 fell during hyperventilation, there was a rise in Ros.

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NMR measurements coupled with pattern recognition methods provide a straightforward approach to inspect the disease metabolic status and the preliminary screening tool of marker candidates for further development. COQ4 mutations cause a broad spectrum of mitochondrial disorders associated with CoQ10 deficiency. The 45,X cell population, that most likely is also present in other tissues of the mother, might have protected her from developing MLS. Seven loci control both pathological and immunological tryptanol 25 mg fibromyalgia support parameters, 10 influence immunological parameters only.

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The involvement of calcitonin in the reproductive physiology of the rainbow trout. Therefore, in order to see if there is any association between these two PG-mediate conditions, the incidence of dysmenorrhea anabact gelish gel in 177 primiparous women with threatened premature labor was compared with that in 177 primiparous women without premature uterine contractions. Animals through an efficient excretory system eliminate transformation products via the urine and feces.

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RVFW mass was used as an index of hypertrophy (RVH) and RVFW area was used as an index of dilatation (RVD). Capillary electrophoresis in classical and carrier metrocreme 0 75 erfahrungen ampholytes-based background electrolytes applied to separation and characterization of gonadotropin-releasing hormones. The results show that EPO is effective even when given after the appearance of clinical signs of EAE, but with a reduced efficacy compared to the preventative schedule. Colour genes (R and Rc) for grain and coleoptile upregulate flavonoid biosynthesis genes in wheat.

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This study investigated the role of category-preferential visual processing regions in associative memory across development using a paired associate learning task in a sample of 56 youths (age 6-19 years). Scintigraphy serves as a reliable criterion for the evaluation of the therapeutic efficacy in patients with chronic fimoxyclav dose pyelonephritis (CP).

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The most potent ARE-luciferase inducer was chosen to further examine its effect on Nrf2 and detoxification genes in lamotrigine pill markings m357 HepG2 cells. Many studies using different methodologies have tried to estimate cervical spine motion.